Aug 292012
 

Diarrhea is a common presenting complaint in pediatric practice and following questions are important to be asked from the parent as these help in determining the condition of the child and the cause of diarrhea.

Immediate Questions

1. How old is patient?

In a young infant the intestinal mucosa tends to be more permeable to water than in an older child or adult. This can result in greater net fluid and electrolyte losses. Diarrhea in the first few months of life requires more immediate attention.

2.What are the vital signs?

Tachycardia suggests volume depletion. Hypotension suggests hypovolemic or septic shock. fever implies an infectious etiology. Diarrhea with associated tachycardia, hypotension or fever should be evaluated immediately.

3. Is diarrhea grossly bloody?

Bloody diarrhea is caused by invasive bacterial infections, ischemic bowel or infarction, allergic phenomenon or inflammatory bowel disease. It requires more active and immediate intervention.

4. Is this acute or chronic problem?

Acute diarrhea: Usually a self limited disease, which can often be treated symptomatically. The most common cause is infection. Other common causes include drugs e.g antibiotics as well as excessive intake of high carbohydrate fluids or non absorbable fillers (e.g sorbitol).

Chronic diarrhea: defined as diarrhea that lasts longer than 4 weeks. Common causes include chronic non specific diarrhea (toddler’s diarrhea), lactose intolerance, milk-protein allergy, encopresis, irritable bowel syndrome, various infections, drugs and IBD. It can also present as an acute exacerbation.

5. Are there risk factors that suggest a specific cause? 

Risk factors include day care, winter season, ill contacts, drugs, travel, animal exposure, constipation, excessive juice intake, poorly perpared or stored poultry or salads, untreated water sources, prior abdominal surgery, immunodeficiency and prematurity. Continue reading »

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Aug 112012
 

Children may present with diarrhea which is defined as the passage of loose stools. It is a very common complaint and a list of differential diagnosis should be kept in mind while dealing with a child presenting with this problem.

1. Infection

Viral: Usually resolves in a few days and can be treated symptomatically. Rotavirus, adenovirus and Norwalk virus are more common.

Bacterial: Shigella, salmonella, Campylobacter, E coli , Vibrio, Clostridium species are commonly involved. Spectrum of illness may range from asymptomatic to life threatening. Staph aureus and C perfringens are often associated with food poisoning. Enterohemorrhagic E coli causes bloody diarrhea and may be associated with hemolytic uremic syndrome.

Parasitic: Giardia is often contracted by drinking contaminated water and can cause abdominal distension, diarrhea and at times failure to thrive. Giardia is easily passed through fecal oral route and is common in day care centers. Entamoeba histolytica produces severe coilitis.

2.Postinfectious State

Several viruses can cause severe enteritis resulting in prolonged intestinal mucosal damage, acquired carbohydrate intolerance and malabsorption in infants.

3. Drugs

Antibiotics: Can alter bowel flora and cause loose watery stools. Broad spectrum antibiotics like clindamycin can lead to induction of C difficle overgrowth leading to pseudomembranous colitis.

Laxatives:

Antacids: Magnesium containing antacids can cause osmotic diarrhea.

Cholinergic agents: Metoclopramide and bethenacol are frequently used in children with GERD and may cause significant diarrhea.

Chemotherapy: Mucositis and enteritis can follow radiation and chemotherapy.

4. Diet

Overfeeding:

Adverse reaction or allergy to some food items Continue reading »

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Aug 012012
 

Cyclic vomiting syndrome (CVS) is a rare disorder characterized by recurrent episodes of severe nausea and vomiting. An episode may last for a few hours to several days and then is followed by a period of time during which affected individuals are free of severe nausea and vomiting. This alternating pattern of disease and disease-free periods distinguishes cyclic vomiting syndrome from other similar disorders.

Cyclic vomiting syndrome (CVS) is a chronic functional disorder of unknown etiology that is characterized by paroxysmal, recurrent episodes of vomiting. The pathophysiology is unknown, but data suggest a strong genetic component.

Cyclic vomiting usually develops during childhood usually ages 3–7; although it often remits during adolescence, it can persist into adult life.

Epidemiology

Cyclic vomiting syndrome occurs in all races but seems to disproportionately affect whites.

Females show a slight predominance over males.

Causes and Risk Factors

The cause of cyclic vomiting syndrome is unknown, but the bouts of vomiting that characterize the condition can be triggered by:

  • Colds, allergies or sinus problems
  • Emotional stress or excitement
  • Foods such as chocolate or cheese
  • Overeating or eating right before going to bed
  • Hot weather
  • Physical exhaustion
Many children who have cyclic vomiting syndrome have a family history of migraines or begin having migraines themselves when they get older. Abdominal migraine — a type of migraine more common in children — causes abdominal pain but not the severe vomiting associated with cyclic vomiting syndrome.

Four Phases Of CVS

CVS has four phases:

  • Symptom-free interval phase. This phase is the period between episodes when no symptoms are present.
  • Prodrome phase. This phase signals that an episode of nausea and vomiting is about to begin. Often marked by nausea—with or without abdominal pain—this phase can last from just a few minutes to several hours. Sometimes, taking medicine early in the phase can stop an episode in progress. However, sometimes there is no warning; a person may simply wake up in the morning and begin vomiting.
  • Vomiting phase. This phase consists of nausea and vomiting; an inability to eat, drink, or take medicines without vomiting; paleness; drowsiness; and exhaustion.
  • Recovery phase. This phase begins when the nausea and vomiting stop. Healthy color, appetite, and energy return.

Clinical Signs and Symptoms

Cyclic vomiting syndrome causes: Continue reading »

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