Juvenile rheumatoid arthritis (JRA) is a common, rheumatic disease of children and a major cause of chronic disability. It is characterized by a synovitis of the peripheral joints manifesting in soft tissue swelling and effusion.
In the Classification Criteria of the American College of Rheumatology (ACR), JRA is regarded not as a single disease but as a category of diseases with three principal types of onset:
(1) oligoarthritis or pauciarticular disease,
(2) polyarthritis, and
(3) systemic-onset disease.
Initial symptoms may be subtle or acute, and often include morning stiffness and gelling, easy fatigability, particularly after school in the early afternoon, joint pain later in the day, and objective joint swelling. The involved joints are often warm, resist full range of motion, are painful on motion, but are not usually erythematous.
Oligoarthritis (pauciarticular disease) predominantly affects the joints of the lower extremities, such as the knees and ankles . Often, only a single joint is involved at onset. Isolated involvement of upper extremity large joints is not characteristic of this type of onset. Involvement of the hip is almost never a presenting sign of JRA. Hip disease may occur later, particularly in polyarticular JRA, and is often a component of a deteriorating functional course.
Polyarthritis (polyarticular disease) is generally characterized by involvement of both large Continue reading »
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